Little Difference Seen in Asthma Strategies – NYTimes.com
There has been no general agreement on the best way to adjust the dosage of inhaled corticosteroids used by adults with asthma. Doctors determine the dose by assessing symptoms like lung function or by using biomarkers like exhaled nitric oxide, or they simply let patients decide how much is needed.
A study published last week in The Journal of the American Medical Association found little difference in the three methods.
Researchers randomly assigned 342 adults with mild to moderate asthma to three groups. Those in the first had their doses adjusted by symptom assessment and those in the second by nitric oxide measurement. Those in the third group were allowed to decide on their own. The scientists recorded how long it took before a mild asthma attack occurred.